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KMID : 0358920110380020155
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Journal of the Korean Academy of Pedodontics
2011 Volume.38 No. 2 p.155 ~ p.160
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The influence of Lactobacillus rhamnosus GG on the binding ability of Streptococcus mutans
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Lee Soo-Jin
Lee Sung-Hoon
Choi Bong-Kyu
Kim Jung-Wook
Kim Young-Jae
Kim Chong-Chul
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Abstract
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Probiotics has currently attracted for means of preventive treatment measurement instead of using non-specific and broad spectrum antimicrobials. In previous studies, two main probiotics species, Lactobacillus and Bifidobateria, showed the reduction of DMFS and S. mutans counts. However, the timing of introducing probiotic species to oral cavity is not clear. The aim of this study is to evaluate the changes of binding ability of S. mutans in various concentrations and inoculation time of L. rhamnosus GG. Adding the following concentration of L. rhamnosus GG, 1×10^6 CFU, 1×10^7 CFU and 1×10^8 CFU, to S. mutans medium demonstrates significant reduction of S. mutans counts. Additionally, more reduction was observed when L. rhamnosus were inoculated prior to S. mutans or simultaneously inoculated compared to when S. mutans were inoculated prior to L. rhamnosus after 3 hours of incubation. Based on this research, the timing of introducing probiotics should be considered when probiotics are utilized as a preventive treatment measurement.
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KEYWORD
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Probiotics, Lactobacillus rhamnosus, Streptococcus mutans
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